TargetNet
P31648
Sodium- and chloride-dependent GABA transporter 1
Function
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
Database Links
| Database | Links |
|---|---|
| UniProt | P31648 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P31648 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | mmu:232333 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 232333 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9856 | 0.0111 |
| Accuracy | 0.9316 | 0.0067 |
| Sensitivity | 0.902 | 0.0042 |
| Specificity | 0.9594 | 0.0118 |
| BEDROC | 0.9999 | 3.6485 × 10-5 |
| MCC Threshold | 0.418 | N/A |
| MCC | 0.8931 | N/A |
| F-score Threshold | 0.418 | N/A |
| F-score | 0.9447 | N/A |