Histamine H1 receptor
In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
Database | Links |
---|---|
UniProt | P31390 |
PDB | Not available |
BioGrid | Not available |
BindingDB | P31390 |
DrugBank | Not available |
Guide to PHARMACOLOGY | 262 |
PharmGKB | Not available |
KEGG | rno:24448 |
BioCyc | Not available |
Entrez Gene (GeneID) | 24448 |
Metric | Mean Value | Standard Deviation |
---|---|---|
AUC | 0.9238 | 0.0064 |
Accuracy | 0.8604 | 0.0088 |
Sensitivity | 0.8733 | 0.0154 |
Specificity | 0.8454 | 0.0143 |
BEDROC | 0.9734 | 0.0106 |
MCC Threshold | 0.494 | N/A |
MCC | 0.7365 | N/A |
F-score Threshold | 0.488 | N/A |
F-score | 0.8782 | N/A |