TargetNet
P30989
Neurotensin receptor type 1
Function
Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol- calcium second messenger system.
Database Links
| Database | Links |
|---|---|
| UniProt | P30989 |
| PDB | 2LYW |
| BioGrid | 110977 |
| BindingDB | P30989 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 309 |
| PharmGKB | PA31821 |
| KEGG | hsa:4923 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 4923 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.7703 | 0.0115 |
| Accuracy | 0.7278 | 0.0121 |
| Sensitivity | 0.62 | 0.0187 |
| Specificity | 0.8414 | 0.0192 |
| BEDROC | 0.9907 | 0.0071 |
| MCC Threshold | 0.766 | N/A |
| MCC | 0.5667 | N/A |
| F-score Threshold | 0.47 | N/A |
| F-score | 0.7344 | N/A |