TargetNet
P30729
D(4) dopamine receptor
Function
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity).
Database Links
| Database | Links |
|---|---|
| UniProt | P30729 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P30729 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 217 |
| PharmGKB | Not available |
| KEGG | rno:25432 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 25432 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9634 | 0.0031 |
| Accuracy | 0.9134 | 0.0085 |
| Sensitivity | 0.9035 | 0.0089 |
| Specificity | 0.9227 | 0.0138 |
| BEDROC | 0.9995 | 1.5604 × 10-4 |
| MCC Threshold | 0.57 | N/A |
| MCC | 0.8483 | N/A |
| F-score Threshold | 0.57 | N/A |
| F-score | 0.9164 | N/A |