TargetNet
P30560
Vasopressin V1a receptor
Function
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Involved in social memory formation.
Database Links
| Database | Links |
|---|---|
| UniProt | P30560 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P30560 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 366 |
| PharmGKB | Not available |
| KEGG | rno:25107 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 25107 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9789 | 0.0016 |
| Accuracy | 0.9386 | 0.0039 |
| Sensitivity | 0.9475 | 0.0079 |
| Specificity | 0.9312 | 0.0036 |
| BEDROC | 0.9985 | 5.0459 × 10-4 |
| MCC Threshold | 0.486 | N/A |
| MCC | 0.8876 | N/A |
| F-score Threshold | 0.486 | N/A |
| F-score | 0.9398 | N/A |