TargetNet


P30559

Oxytocin receptor


Function

Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system.


Database Links

Database Links
UniProt P30559
PDB Not available
BioGrid 111061
BindingDB P30559
DrugBank DB01282
Guide to PHARMACOLOGY 369
PharmGKB PA32858
KEGG hsa:5021
BioCyc Not available
Entrez Gene (GeneID) 5021

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.9703 0.0029
Accuracy 0.926 0.0037
Sensitivity 0.9145 0.0066
Specificity 0.9375 0.0031
BEDROC 0.9997 8.8307 × 10-5
MCC Threshold 0.472 N/A
MCC 0.8568 N/A
F-score Threshold 0.472 N/A
F-score 0.9279 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:33