TargetNet
P30556
Type-1 angiotensin II receptor
Function
Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
Database Links
| Database | Links |
|---|---|
| UniProt | P30556 |
| PDB | 1ZV0 |
| BioGrid | 106691 |
| BindingDB | P30556 |
| DrugBank | DB00796, DB00876, DB01342, DB01029, DB00678, DB00275, DB01347, DB00421, DB01349, DB00966, DB00177 |
| Guide to PHARMACOLOGY | 34 |
| PharmGKB | PA43 |
| KEGG | hsa:185 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 185 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9795 | 6.5285 × 10-4 |
| Accuracy | 0.9547 | 0.0011 |
| Sensitivity | 0.9307 | 0.0026 |
| Specificity | 0.9801 | 0.0012 |
| BEDROC | 0.9997 | 4.6723 × 10-4 |
| MCC Threshold | 0.39 | N/A |
| MCC | 0.9165 | N/A |
| F-score Threshold | 0.39 | N/A |
| F-score | 0.9585 | N/A |