TargetNet
P30543
Adenosine receptor A2a
Function
Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | P30543 |
| PDB | Not available |
| BioGrid | 247408 |
| BindingDB | P30543 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 19 |
| PharmGKB | Not available |
| KEGG | rno:25369 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 25369 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9723 | 7.1634 × 10-4 |
| Accuracy | 0.9203 | 0.0029 |
| Sensitivity | 0.9296 | 0.0039 |
| Specificity | 0.9091 | 0.003 |
| BEDROC | 0.9945 | 0.0031 |
| MCC Threshold | 0.37 | N/A |
| MCC | 0.849 | N/A |
| F-score Threshold | 0.37 | N/A |
| F-score | 0.9332 | N/A |