TargetNet
P30542
Adenosine receptor A1
Function
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | P30542 |
| PDB | Not available |
| BioGrid | 106646 |
| BindingDB | P30542 |
| DrugBank | DB01223, DB00201, DB04932, DB00996, DB00458, DB00061, DB00277 |
| Guide to PHARMACOLOGY | 18 |
| PharmGKB | PA24583 |
| KEGG | hsa:134 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 134 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9844 | 6.3453 × 10-4 |
| Accuracy | 0.9491 | 9.6044 × 10-4 |
| Sensitivity | 0.9509 | 0.0017 |
| Specificity | 0.9476 | 0.0013 |
| BEDROC | 0.9975 | 0.0015 |
| MCC Threshold | 0.46 | N/A |
| MCC | 0.9001 | N/A |
| F-score Threshold | 0.46 | N/A |
| F-score | 0.9473 | N/A |