TargetNet
P30518
Vasopressin V2 receptor
Function
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.
Database Links
| Database | Links |
|---|---|
| UniProt | P30518 |
| PDB | 4JQI |
| BioGrid | 107035 |
| BindingDB | P30518 |
| DrugBank | DB00872, DB02638, DB00067 |
| Guide to PHARMACOLOGY | 368 |
| PharmGKB | PA25189 |
| KEGG | hsa:554 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 554 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9705 | 0.002 |
| Accuracy | 0.9308 | 0.0038 |
| Sensitivity | 0.9162 | 0.0075 |
| Specificity | 0.9444 | 0.0038 |
| BEDROC | 0.9895 | 0.0027 |
| MCC Threshold | 0.474 | N/A |
| MCC | 0.8612 | N/A |
| F-score Threshold | 0.474 | N/A |
| F-score | 0.9272 | N/A |