TargetNet
P30411
B2 bradykinin receptor
Function
Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Database Links
| Database | Links |
|---|---|
| UniProt | P30411 |
| PDB | Not available |
| BioGrid | 107093 |
| BindingDB | P30411 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 42 |
| PharmGKB | PA80 |
| KEGG | hsa:624 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 624 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9884 | 0.0018 |
| Accuracy | 0.96 | 0.003 |
| Sensitivity | 0.9473 | 0.0045 |
| Specificity | 0.9725 | 0.0034 |
| BEDROC | 0.9989 | 0.0011 |
| MCC Threshold | 0.416 | N/A |
| MCC | 0.9269 | N/A |
| F-score Threshold | 0.326 | N/A |
| F-score | 0.9633 | N/A |