TargetNet
P29275
Adenosine receptor A2b
Function
Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | P29275 |
| PDB | Not available |
| BioGrid | 106648 |
| BindingDB | P29275 |
| DrugBank | DB04932, DB00824, DB00061, DB00277 |
| Guide to PHARMACOLOGY | 20 |
| PharmGKB | PA24585 |
| KEGG | hsa:136 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 136 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9874 | 3.4256 × 10-4 |
| Accuracy | 0.9542 | 0.0018 |
| Sensitivity | 0.9592 | 0.0023 |
| Specificity | 0.948 | 0.0032 |
| BEDROC | 0.9997 | 2.4688 × 10-4 |
| MCC Threshold | 0.436 | N/A |
| MCC | 0.9104 | N/A |
| F-score Threshold | 0.436 | N/A |
| F-score | 0.96 | N/A |