TargetNet
P29089
Type-1B angiotensin II receptor
Function
Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
Database Links
| Database | Links |
|---|---|
| UniProt | P29089 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P29089 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 34 |
| PharmGKB | Not available |
| KEGG | rno:81638 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 81638 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9883 | 0.0013 |
| Accuracy | 0.9639 | 0.0026 |
| Sensitivity | 0.9777 | 0.0048 |
| Specificity | 0.9493 | 0.0032 |
| BEDROC | 0.9955 | 0.003 |
| MCC Threshold | 0.474 | N/A |
| MCC | 0.9362 | N/A |
| F-score Threshold | 0.474 | N/A |
| F-score | 0.9693 | N/A |