TargetNet
P28647
Adenosine receptor A3
Function
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.
Database Links
| Database | Links |
|---|---|
| UniProt | P28647 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P28647 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 21 |
| PharmGKB | Not available |
| KEGG | rno:100911796, rno:25370 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 100911796, 25370 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9405 | 0.0095 |
| Accuracy | 0.8745 | 0.008 |
| Sensitivity | 0.8592 | 0.0171 |
| Specificity | 0.8884 | 0.0102 |
| BEDROC | 0.9965 | 0.0014 |
| MCC Threshold | 0.522 | N/A |
| MCC | 0.7445 | N/A |
| F-score Threshold | 0.284 | N/A |
| F-score | 0.8709 | N/A |