TargetNet
P25104
Type-1 angiotensin II receptor
Function
Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
Database Links
| Database | Links |
|---|---|
| UniProt | P25104 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P25104 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | bta:281607 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 281607 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9884 | 0.0023 |
| Accuracy | 0.9685 | 0.0051 |
| Sensitivity | 0.9833 | 0.0103 |
| Specificity | 0.9559 | 0.0024 |
| BEDROC | 0.9926 | 0.0158 |
| MCC Threshold | 0.486 | N/A |
| MCC | 0.9517 | N/A |
| F-score Threshold | 0.486 | N/A |
| F-score | 0.9741 | N/A |