TargetNet
P25100
Alpha-1D adrenergic receptor
Function
This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.
Database Links
| Database | Links |
|---|---|
| UniProt | P25100 |
| PDB | Not available |
| BioGrid | 106656 |
| BindingDB | P25100 |
| DrugBank | DB00346, DB00217, DB00298, DB04840, DB00590, DB00226, DB01170, DB01403, DB00368, DB00420, DB01608, DB00777, DB06144, DB00706, DB01162 |
| Guide to PHARMACOLOGY | 24 |
| PharmGKB | PA24597 |
| KEGG | hsa:146 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 146 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9726 | 0.0024 |
| Accuracy | 0.9407 | 0.0017 |
| Sensitivity | 0.9211 | 0.0036 |
| Specificity | 0.9613 | 0.0033 |
| BEDROC | 0.9931 | 0.003 |
| MCC Threshold | 0.468 | N/A |
| MCC | 0.8864 | N/A |
| F-score Threshold | 0.468 | N/A |
| F-score | 0.9436 | N/A |