TargetNet
P25099
Adenosine receptor A1
Function
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | P25099 |
| PDB | Not available |
| BioGrid | 247960 |
| BindingDB | P25099 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 18 |
| PharmGKB | Not available |
| KEGG | rno:29290 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 29290 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9539 | 0.0015 |
| Accuracy | 0.8988 | 0.0037 |
| Sensitivity | 0.9144 | 0.006 |
| Specificity | 0.8797 | 0.0023 |
| BEDROC | 0.9761 | 0.0052 |
| MCC Threshold | 0.316 | N/A |
| MCC | 0.7945 | N/A |
| F-score Threshold | 0.316 | N/A |
| F-score | 0.9113 | N/A |