TargetNet
P23978
Sodium- and chloride-dependent GABA transporter 1
Function
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
Database Links
| Database | Links |
|---|---|
| UniProt | P23978 |
| PDB | Not available |
| BioGrid | 249421 |
| BindingDB | P23978 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | rno:79212 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 79212 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9772 | 0.008 |
| Accuracy | 0.9299 | 0.0082 |
| Sensitivity | 0.904 | 0.0107 |
| Specificity | 0.9526 | 0.0085 |
| BEDROC | 0.9999 | 1.8267 × 10-5 |
| MCC Threshold | 0.77 | N/A |
| MCC | 0.8733 | N/A |
| F-score Threshold | 0.77 | N/A |
| F-score | 0.9255 | N/A |