TargetNet
P23977
Sodium-dependent dopamine transporter
Function
Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
Database Links
| Database | Links |
|---|---|
| UniProt | P23977 |
| PDB | Not available |
| BioGrid | 247007 |
| BindingDB | P23977 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | rno:24898 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 24898 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9779 | 7.6423 × 10-4 |
| Accuracy | 0.9351 | 0.001 |
| Sensitivity | 0.9379 | 0.0019 |
| Specificity | 0.9323 | 0.0014 |
| BEDROC | 0.9953 | 0.0026 |
| MCC Threshold | 0.494 | N/A |
| MCC | 0.872 | N/A |
| F-score Threshold | 0.494 | N/A |
| F-score | 0.9361 | N/A |