TargetNet


P23944

Alpha-1D adrenergic receptor


Function

This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.


Database Links

Database Links
UniProt P23944
PDB Not available
BioGrid Not available
BindingDB P23944
DrugBank Not available
Guide to PHARMACOLOGY 24
PharmGKB Not available
KEGG rno:29413
BioCyc Not available
Entrez Gene (GeneID) 29413

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.9638 0.004
Accuracy 0.9248 0.0069
Sensitivity 0.9221 0.0093
Specificity 0.9278 0.0049
BEDROC 0.9999 8.3717 × 10-5
MCC Threshold 0.526 N/A
MCC 0.8657 N/A
F-score Threshold 0.526 N/A
F-score 0.9355 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:29