TargetNet
P23795
Acetylcholinesterase
Function
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
Database Links
| Database | Links |
|---|---|
| UniProt | P23795 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P23795 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | bta:540446 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 540446 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9594 | 0.0046 |
| Accuracy | 0.916 | 0.0102 |
| Sensitivity | 0.9114 | 0.0136 |
| Specificity | 0.9214 | 0.0116 |
| BEDROC | 0.9998 | 8.8268 × 10-5 |
| MCC Threshold | 0.534 | N/A |
| MCC | 0.8731 | N/A |
| F-score Threshold | 0.534 | N/A |
| F-score | 0.9394 | N/A |