TargetNet
P23219
Prostaglandin G/H synthase 1
Function
May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.
Database Links
| Database | Links |
|---|---|
| UniProt | P23219 |
| PDB | Not available |
| BioGrid | 111714 |
| BindingDB | P23219 |
| DrugBank | DB00316, DB00945, DB01014, DB00963, DB01188, DB00586, DB00861, DB04817, DB00749, DB00573, DB00712, DB00154, DB01050, DB00159, DB00328, DB01009, DB00465, DB01283, DB00939, DB00784, DB00244, DB00350, DB00461, DB00788, DB03783, DB00554, DB00533, DB00936, DB01399, DB00605, DB00870, DB00469, DB00500 |
| Guide to PHARMACOLOGY | 1375 |
| PharmGKB | PA24346 |
| KEGG | hsa:5742 |
| BioCyc | MetaCyc:HS01815-MONOMER |
| Entrez Gene (GeneID) | 5742 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.8077 | 0.0135 |
| Accuracy | 0.7203 | 0.0125 |
| Sensitivity | 0.6841 | 0.0238 |
| Specificity | 0.756 | 0.0197 |
| BEDROC | 0.9614 | 0.0145 |
| MCC Threshold | 0.652 | N/A |
| MCC | 0.4921 | N/A |
| F-score Threshold | 0.334 | N/A |
| F-score | 0.7636 | N/A |