TargetNet
P21980
Protein-glutamine gamma-glutamyltransferase 2
Function
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
Database Links
| Database | Links |
|---|---|
| UniProt | P21980 |
| PDB | 1FAU, 1KV3, 2Q3Z, 3LY6, 3S3J, 3S3P, 3S3S |
| BioGrid | 112910 |
| BindingDB | P21980 |
| DrugBank | DB00130 |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | PA36491 |
| KEGG | hsa:7052 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 7052 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9268 | 0.0082 |
| Accuracy | 0.886 | 0.0061 |
| Sensitivity | 0.8847 | 0.0091 |
| Specificity | 0.8874 | 0.0078 |
| BEDROC | 0.9777 | 0.0081 |
| MCC Threshold | 0.442 | N/A |
| MCC | 0.7814 | N/A |
| F-score Threshold | 0.442 | N/A |
| F-score | 0.8943 | N/A |