TargetNet
P21918
D(1B) dopamine receptor
Function
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | P21918 |
| PDB | Not available |
| BioGrid | 108150 |
| BindingDB | P21918 |
| DrugBank | DB00714, DB01038, DB00800, DB01624 |
| Guide to PHARMACOLOGY | 218 |
| PharmGKB | PA148 |
| KEGG | hsa:1816 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 1816 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.8503 | 0.0083 |
| Accuracy | 0.7652 | 0.0134 |
| Sensitivity | 0.749 | 0.0201 |
| Specificity | 0.7842 | 0.0177 |
| BEDROC | 0.9927 | 0.0038 |
| MCC Threshold | 0.472 | N/A |
| MCC | 0.5832 | N/A |
| F-score Threshold | 0.472 | N/A |
| F-score | 0.8111 | N/A |