TargetNet
P21728
D(1A) dopamine receptor
Function
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | P21728 |
| PDB | 1OZ5 |
| BioGrid | 108146 |
| BindingDB | P21728 |
| DrugBank | DB01063, DB00915, DB00714, DB01038, DB01239, DB00363, DB00907, DB00988, DB00800, DB00875, DB00623, DB00502, DB01235, DB00589, DB00408, DB00353, DB00805, DB00334, DB00061, DB01186, DB00850, DB00433, DB00420, DB00777, DB01224, DB00372, DB00679, DB00508, DB01624 |
| Guide to PHARMACOLOGY | 214 |
| PharmGKB | PA147 |
| KEGG | hsa:1812 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 1812 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9135 | 0.0019 |
| Accuracy | 0.8422 | 0.0036 |
| Sensitivity | 0.8004 | 0.0055 |
| Specificity | 0.8919 | 0.0052 |
| BEDROC | 0.9906 | 0.0016 |
| MCC Threshold | 0.488 | N/A |
| MCC | 0.6934 | N/A |
| F-score Threshold | 0.438 | N/A |
| F-score | 0.8548 | N/A |