TargetNet
P19156
Potassium-transporting ATPase alpha chain 1
Function
Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
Database Links
| Database | Links |
|---|---|
| UniProt | P19156 |
| PDB | 1IWC, 1IWF, 2XZB, 2YN9, 3IXZ |
| BioGrid | Not available |
| BindingDB | P19156 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | ssc:397552 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 397552 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9475 | 0.0045 |
| Accuracy | 0.878 | 0.0101 |
| Sensitivity | 0.9126 | 0.0097 |
| Specificity | 0.8356 | 0.0149 |
| BEDROC | 0.9991 | 2.7334 × 10-4 |
| MCC Threshold | 0.584 | N/A |
| MCC | 0.7754 | N/A |
| F-score Threshold | 0.404 | N/A |
| F-score | 0.9018 | N/A |