TargetNet
P19020
D(3) dopamine receptor
Function
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).
Database Links
| Database | Links |
|---|---|
| UniProt | P19020 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P19020 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 216 |
| PharmGKB | Not available |
| KEGG | rno:29238 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 29238 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9768 | 0.0014 |
| Accuracy | 0.9347 | 0.0029 |
| Sensitivity | 0.9446 | 0.005 |
| Specificity | 0.923 | 0.0058 |
| BEDROC | 0.993 | 0.0047 |
| MCC Threshold | 0.47 | N/A |
| MCC | 0.8823 | N/A |
| F-score Threshold | 0.47 | N/A |
| F-score | 0.9468 | N/A |