TargetNet
P18084
Integrin beta-5
Function
Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Database Links
| Database | Links |
|---|---|
| UniProt | P18084 |
| PDB | Not available |
| BioGrid | 109899 |
| BindingDB | P18084 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | PA29959 |
| KEGG | hsa:3693 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 3693 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9789 | 0.004 |
| Accuracy | 0.9212 | 0.0087 |
| Sensitivity | 0.9321 | 0.0133 |
| Specificity | 0.9118 | 0.0085 |
| BEDROC | 0.9956 | 0.0025 |
| MCC Threshold | 0.278 | N/A |
| MCC | 0.8648 | N/A |
| F-score Threshold | 0.278 | N/A |
| F-score | 0.928 | N/A |