TargetNet
P16116
Aldose reductase
Function
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
Database Links
| Database | Links |
|---|---|
| UniProt | P16116 |
| PDB | 2GO6 |
| BioGrid | Not available |
| BindingDB | P16116 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | Not available |
| BioCyc | Not available |
| Entrez Gene (GeneID) | Not available |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9052 | 0.0079 |
| Accuracy | 0.8127 | 0.0111 |
| Sensitivity | 0.8276 | 0.0134 |
| Specificity | 0.7968 | 0.02 |
| BEDROC | 0.9981 | 9.1314 × 10-4 |
| MCC Threshold | 0.718 | N/A |
| MCC | 0.6487 | N/A |
| F-score Threshold | 0.416 | N/A |
| F-score | 0.8169 | N/A |