TargetNet


P11597

Cholesteryl ester transfer protein


Function

Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol.


Database Links

Database Links
UniProt P11597
PDB 2OBD, 4EWS, 4F2A
BioGrid 107498
BindingDB P11597
DrugBank Not available
Guide to PHARMACOLOGY Not available
PharmGKB PA108
KEGG hsa:1071
BioCyc Not available
Entrez Gene (GeneID) 1071

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.9255 0.0033
Accuracy 0.8635 0.0051
Sensitivity 0.8822 0.0094
Specificity 0.8466 0.004
BEDROC 0.9635 0.0165
MCC Threshold 0.488 N/A
MCC 0.7393 N/A
F-score Threshold 0.488 N/A
F-score 0.8662 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:23