TargetNet
P11086
Phenylethanolamine N-methyltransferase
Function
Converts noradrenaline to adrenaline.
Database Links
| Database | Links |
|---|---|
| UniProt | P11086 |
| PDB | 1HNN, 1N7I, 1N7J, 1YZ3, 2AN3, 2AN4, 2AN5, 2G70, 2G71, 2G72, 2G8N, 2OBF, 2ONY, 2ONZ, 2OPB, 3HCA, 3HCB, 3HCC, 3HCD, 3HCE, 3HCF, 3KPJ, 3KPU, 3KPV, 3KPW, 3KPY, 3KQM, 3KQO, 3KQP, 3KQQ, 3KQS, 3KQT, 3KQV, 3KQW, 3KQY, 3KR0, 3KR1, 3KR2, 4DM3 |
| BioGrid | 111410 |
| BindingDB | P11086 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 2496 |
| PharmGKB | PA274 |
| KEGG | hsa:5409 |
| BioCyc | MetaCyc:HS06868-MONOMER |
| Entrez Gene (GeneID) | 5409 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.8417 | 0.0154 |
| Accuracy | 0.7732 | 0.0146 |
| Sensitivity | 0.8389 | 0.024 |
| Specificity | 0.7 | 0.0157 |
| BEDROC | 0.9324 | 0.0435 |
| MCC Threshold | 0.362 | N/A |
| MCC | 0.5672 | N/A |
| F-score Threshold | 0.362 | N/A |
| F-score | 0.8101 | N/A |