TargetNet
P09237
Matrilysin
Function
Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
Database Links
| Database | Links |
|---|---|
| UniProt | P09237 |
| PDB | 1MMP, 1MMQ, 1MMR, 2DDY, 2Y6C, 2Y6D |
| BioGrid | 110459 |
| BindingDB | P09237 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | PA30887 |
| KEGG | hsa:4316 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 4316 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9327 | 0.0032 |
| Accuracy | 0.8764 | 0.0072 |
| Sensitivity | 0.9121 | 0.0119 |
| Specificity | 0.8365 | 0.0079 |
| BEDROC | 0.9564 | 0.0156 |
| MCC Threshold | 0.496 | N/A |
| MCC | 0.7809 | N/A |
| F-score Threshold | 0.496 | N/A |
| F-score | 0.899 | N/A |