Muscarinic acetylcholine receptor M5
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Database | Links |
---|---|
UniProt | P08912 |
PDB | Not available |
BioGrid | Not available |
BindingDB | P08912 |
DrugBank | DB00572, DB00767, DB00785, DB00725, DB01403, DB00340, DB00334, DB00420, DB01069, DB00777, DB00372 |
Guide to PHARMACOLOGY | 17 |
PharmGKB | PA26486 |
KEGG | hsa:1133 |
BioCyc | Not available |
Entrez Gene (GeneID) | 1133 |
Metric | Mean Value | Standard Deviation |
---|---|---|
AUC | 0.8516 | 0.0091 |
Accuracy | 0.7798 | 0.0112 |
Sensitivity | 0.7955 | 0.0194 |
Specificity | 0.7639 | 0.007 |
BEDROC | 0.9614 | 0.0081 |
MCC Threshold | 0.532 | N/A |
MCC | 0.5463 | N/A |
F-score Threshold | 0.37 | N/A |
F-score | 0.7738 | N/A |