TargetNet


P08842

Steryl-sulfatase


Function

Conversion of sulfated steroid precursors to estrogens during pregnancy.


Database Links

Database Links
UniProt P08842
PDB 1P49
BioGrid Not available
BindingDB P08842
DrugBank DB00655
Guide to PHARMACOLOGY Not available
PharmGKB PA36225
KEGG hsa:412
BioCyc Not available
Entrez Gene (GeneID) 412

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.8967 0.0048
Accuracy 0.8283 0.0076
Sensitivity 0.8059 0.0123
Specificity 0.8473 0.0144
BEDROC 0.9487 0.0183
MCC Threshold 0.476 N/A
MCC 0.6774 N/A
F-score Threshold 0.476 N/A
F-score 0.8248 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:22