Muscarinic acetylcholine receptor M1
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Database | Links |
---|---|
UniProt | P08482 |
PDB | Not available |
BioGrid | 247270 |
BindingDB | P08482 |
DrugBank | Not available |
Guide to PHARMACOLOGY | 13 |
PharmGKB | Not available |
KEGG | rno:25229 |
BioCyc | Not available |
Entrez Gene (GeneID) | 25229 |
Metric | Mean Value | Standard Deviation |
---|---|---|
AUC | 0.9393 | 0.0028 |
Accuracy | 0.8839 | 0.0043 |
Sensitivity | 0.8699 | 0.0116 |
Specificity | 0.8962 | 0.0048 |
BEDROC | 0.9919 | 0.0021 |
MCC Threshold | 0.502 | N/A |
MCC | 0.774 | N/A |
F-score Threshold | 0.448 | N/A |
F-score | 0.8801 | N/A |