TargetNet
P07607
Thymidylate synthase
Function
Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity).
Database Links
| Database | Links |
|---|---|
| UniProt | P07607 |
| PDB | 3IHI, 4E5O, 4EB4, 4EIN, 4EZ8 |
| BioGrid | Not available |
| BindingDB | P07607 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | mmu:22171 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 22171 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9789 | 0.0012 |
| Accuracy | 0.9472 | 0.0044 |
| Sensitivity | 0.9594 | 0.0076 |
| Specificity | 0.9365 | 0.0033 |
| BEDROC | 0.9828 | 0.0098 |
| MCC Threshold | 0.24 | N/A |
| MCC | 0.9034 | N/A |
| F-score Threshold | 0.24 | N/A |
| F-score | 0.9492 | N/A |