TargetNet


P07478

Trypsin-2


Function

In the ileum, may be involved in defensin processing, including DEFA5.


Database Links

Database Links
UniProt P07478
PDB Not available
BioGrid 111627
BindingDB P07478
DrugBank Not available
Guide to PHARMACOLOGY Not available
PharmGKB PA33833
KEGG hsa:5645
BioCyc Not available
Entrez Gene (GeneID) 5645

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.9855 0.0019
Accuracy 0.9507 0.0046
Sensitivity 0.9498 0.0081
Specificity 0.9514 0.0066
BEDROC 0.9993 4.8937 × 10-4
MCC Threshold 0.53 N/A
MCC 0.9019 N/A
F-score Threshold 0.514 N/A
F-score 0.9484 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:20