TargetNet


P05979

Prostaglandin G/H synthase 1


Function

May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.


Database Links

Database Links
UniProt P05979
PDB 1CQE, 1DIY, 1DJJ, 1EBV, 1EQG, 1EQH, 1FE2, 1HT5, 1HT8, 1IGX, 1IGZ, 1PGE, 1PGF, 1PGG, 1PRH, 1PTH, 1Q4G, 1U67, 2AYL, 2OYE, 2OYU, 3KK6, 3N8V, 3N8W, 3N8X, 3N8Y, 3N8Z, 4O1Z
BioGrid Not available
BindingDB P05979
DrugBank Not available
Guide to PHARMACOLOGY Not available
PharmGKB Not available
KEGG Not available
BioCyc Not available
Entrez Gene (GeneID) 443551

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.8705 0.005
Accuracy 0.8142 0.0063
Sensitivity 0.8541 0.0139
Specificity 0.7696 0.0146
BEDROC 0.9366 0.0124
MCC Threshold 0.566 N/A
MCC 0.6504 N/A
F-score Threshold 0.564 N/A
F-score 0.8354 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:19