TargetNet
P05364
Beta-lactamase
Function
This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
Database Links
| Database | Links |
|---|---|
| UniProt | P05364 |
| PDB | 1BLS, 1GCE, 1RGZ, 1XX2, 1Y54, 2Q9M, 2Q9N, 3S4X |
| BioGrid | Not available |
| BindingDB | P05364 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | Not available |
| BioCyc | Not available |
| Entrez Gene (GeneID) | Not available |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9365 | 0.0081 |
| Accuracy | 0.8662 | 0.0134 |
| Sensitivity | 0.8537 | 0.0162 |
| Specificity | 0.8794 | 0.0202 |
| BEDROC | 0.9976 | 0.0059 |
| MCC Threshold | 0.454 | N/A |
| MCC | 0.7712 | N/A |
| F-score Threshold | 0.454 | N/A |
| F-score | 0.8889 | N/A |