TargetNet
P05186
Alkaline phosphatase, tissue-nonspecific isozyme
Function
This isozyme may play a role in skeletal mineralization.
Database Links
| Database | Links |
|---|---|
| UniProt | P05186 |
| PDB | Not available |
| BioGrid | 106750 |
| BindingDB | P05186 |
| DrugBank | DB01143 |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | PA24729 |
| KEGG | hsa:249 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 249 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.7917 | 0.0076 |
| Accuracy | 0.7079 | 0.0088 |
| Sensitivity | 0.6579 | 0.0155 |
| Specificity | 0.7633 | 0.0168 |
| BEDROC | 0.9799 | 0.0025 |
| MCC Threshold | 0.58 | N/A |
| MCC | 0.5106 | N/A |
| F-score Threshold | 0.404 | N/A |
| F-score | 0.75 | N/A |