TargetNet
O70536
Sterol O-acyltransferase 1
Function
Catalyzes the formation of fatty acid-cholesterol esters. Plays a role in lipoprotein assembly and dietary cholesterol absorption.
Database Links
| Database | Links |
|---|---|
| UniProt | O70536 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | O70536 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | rno:81782 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 81782 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9665 | 0.0026 |
| Accuracy | 0.9267 | 0.0044 |
| Sensitivity | 0.938 | 0.0068 |
| Specificity | 0.9159 | 0.0073 |
| BEDROC | 0.989 | 0.005 |
| MCC Threshold | 0.432 | N/A |
| MCC | 0.8649 | N/A |
| F-score Threshold | 0.432 | N/A |
| F-score | 0.9321 | N/A |