TargetNet
O60725
Protein-S-isoprenylcysteine O-methyltransferase
Function
Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
Database Links
| Database | Links |
|---|---|
| UniProt | O60725 |
| PDB | Not available |
| BioGrid | 117026 |
| BindingDB | O60725 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | PA29598 |
| KEGG | hsa:23463 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 23463 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9328 | 0.0083 |
| Accuracy | 0.8652 | 0.0145 |
| Sensitivity | 0.8503 | 0.0184 |
| Specificity | 0.8778 | 0.0157 |
| BEDROC | 0.9941 | 0.0016 |
| MCC Threshold | 0.646 | N/A |
| MCC | 0.7607 | N/A |
| F-score Threshold | 0.324 | N/A |
| F-score | 0.8636 | N/A |