TargetNet
O43614
Orexin receptor type 2
Function
Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
Database Links
| Database | Links |
|---|---|
| UniProt | O43614 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | O43614 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 322 |
| PharmGKB | PA29223 |
| KEGG | hsa:3062 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 3062 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9812 | 0.0016 |
| Accuracy | 0.9312 | 0.0044 |
| Sensitivity | 0.9475 | 0.0057 |
| Specificity | 0.9114 | 0.0077 |
| BEDROC | 0.9993 | 4.1261 × 10-4 |
| MCC Threshold | 0.552 | N/A |
| MCC | 0.8797 | N/A |
| F-score Threshold | 0.552 | N/A |
| F-score | 0.9455 | N/A |