TargetNet
O43570
Carbonic anhydrase 12
Function
Reversible hydration of carbon dioxide.
Database Links
| Database | Links |
|---|---|
| UniProt | O43570 |
| PDB | 1JCZ, 1JD0, 4HT2, 4KP5, 4KP8 |
| BioGrid | 107225 |
| BindingDB | O43570 |
| DrugBank | DB00819 |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | PA25987 |
| KEGG | hsa:771 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 771 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9636 | 0.0017 |
| Accuracy | 0.9138 | 0.0034 |
| Sensitivity | 0.9255 | 0.0054 |
| Specificity | 0.9027 | 0.0051 |
| BEDROC | 0.9699 | 0.0031 |
| MCC Threshold | 0.488 | N/A |
| MCC | 0.8328 | N/A |
| F-score Threshold | 0.488 | N/A |
| F-score | 0.9153 | N/A |