TargetNet
O42275
Acetylcholinesterase
Function
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
Database Links
| Database | Links |
|---|---|
| UniProt | O42275 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | O42275 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | Not available |
| BioCyc | Not available |
| Entrez Gene (GeneID) | Not available |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9356 | 0.0018 |
| Accuracy | 0.8801 | 0.0043 |
| Sensitivity | 0.8773 | 0.0058 |
| Specificity | 0.8835 | 0.0053 |
| BEDROC | 0.9971 | 0.0024 |
| MCC Threshold | 0.598 | N/A |
| MCC | 0.7808 | N/A |
| F-score Threshold | 0.598 | N/A |
| F-score | 0.8934 | N/A |