TargetNet
O14939
Phospholipase D2
Function
May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity).
Database Links
| Database | Links |
|---|---|
| UniProt | O14939 |
| PDB | Not available |
| BioGrid | 111354 |
| BindingDB | O14939 |
| DrugBank | DB00122 |
| Guide to PHARMACOLOGY | 1434 |
| PharmGKB | PA33397 |
| KEGG | hsa:5338 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 5338 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.973 | 0.002 |
| Accuracy | 0.9455 | 0.0053 |
| Sensitivity | 0.9687 | 0.0102 |
| Specificity | 0.9215 | 0.0044 |
| BEDROC | 0.9989 | 8.5018 × 10-4 |
| MCC Threshold | 0.434 | N/A |
| MCC | 0.8954 | N/A |
| F-score Threshold | 0.434 | N/A |
| F-score | 0.9493 | N/A |